Forecasting Alert Fatigue in Emergency Department Workflows with Algorithmic Risk Scores

Authors

  • Daniel E. Allen Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, USA Author
  • Daniel Price Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, New York, USA Author

Keywords:

Alert Fatigue, Emergency Department, Risk Scoring Algorithms, Mixed Methods Evaluation, Algorithmic Risk Scores

Abstract

The integration of algorithmic clinical decision support systems in emergency departments has fundamentally transformed patient care by providing real-time risk scores and automated warnings. However, the proliferation of these notifications has precipitated a critical unintended consequence known as alert fatigue, wherein clinicians become desensitized to warnings, leading to increased override rates and potential patient harm. This paper investigates the predictability of alert fatigue derived from algorithmic risk scores through a comprehensive mixed evaluation methodology situated within the complex workflow of a high-acuity emergency department. By synthesizing quantitative data from electronic health record access logs with qualitative insights gathered from clinician shadowing and structured interviews, this research delineates the multifaceted nature of alert fatigue. We propose a framework for understanding how continuous exposure to varying tiers of algorithmic risk scores deteriorates clinical responsiveness. The study identifies key workflow disruptions, cognitive burden indicators, and behavioral adaptations that emergency personnel develop in response to high-frequency alerts. The findings reveal that alert fatigue can be reliably predicted not only by the sheer volume of alerts but by the contextual misalignment between algorithmic risk scores and the dynamic clinical reality of the emergency department. By elucidating the underlying mechanisms of cognitive overload, this paper provides critical insights for the redesign of clinical decision support systems, advocating for context-aware, threshold-calibrated alert mechanisms that prioritize clinician cognitive bandwidth and ultimately safeguard patient safety.

References

1. Yoon, W.J. Endoscopic Transaxillary Augmentation Mammoplasty; Springer: Singapore, 2019.

2. Silicone Breast Implant Modification Review: Overcoming Capsular Contracture | Biomaterials Research. Available online: https://spj.science.org/doi/10.1186/s40824-018-0147-5 (accessed on 7 March 2026).

3. Rai, M.; Yadav, A.; Gade, A. Silver Nanoparticles as a New Generation of Antimicrobials. Biotechnol. Adv. 2009, 27, 76–83.

4. Klasyfikacja wyrobów medycznych—Ministerstwo Zdrowia—Portal Gov.pl. Available online: https://www.gov.pl/web/zdrowie/klasyfikacja-wyrobow-medycznych (accessed on 7 March 2026).

5. Kaoutzanis, C.; Winocour, J.; Unger, J.; Gabriel, A.; Maxwell, G.P. The Evolution of Breast Implants. Semin. Plast. Surg. 2019, 33, 217–223.

6. Piechota, M. Badanie USG piersi z implantami—Kompleksowa diagnostyka w Krakowie. In Proceedings of the BodyMove Kraków 2025, Kraków, Poland, 12–14 2025; BodyMove Kraków: Kraków, Poland, 2025; pp. 12–14.

7. Gouthami, S.; Hegde, N.P. Automatic Sentiment Analysis Scalability Prediction for Information Extraction Using SentiStrength Algorithm. In Proceedings of Third International Conference on Advances in Computer Engineering and Communication Systems; Springer: Singapore, 2023; Volume 612, pp. 21–30. ISBN 978-981-19-9228-5.

8. Drope, J.; Liber, A.C.; Cahn, Z.; Stoklosa, M.; Kennedy, R.; Douglas, C.E.; Henson, R.; Drope, J. Who’s still smoking? Disparities in adult cigarette smoking prevalence in the United States. CA Cancer J. Clin. 2018, 68, 106–115.

9. U.S. Department of Health and Human Services. The Health Consequences of Smoking: 50 Years of Progress. A Report of the Surgeon General; U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health: Atlanta, GA, USA, 2014.

10. Nortey, E.N.; Agyemang, E.F.; Sakyi-Yeboah, E.; Ampomah, O.-A.; Agyekum, L. AI Meets Economics: Can Deep Learning Surpass Machine Learning and Traditional Statistical Models in Inflation Time Series Forecasting? Data Sci. Financ. Econ. 2025, 5, 136–155.

11. Poghosyan, H.; Moen, E.L.; Kim, D.; Manjourides, J.; Cooley, M.E. Social and Structural Determinants of Smoking Status and Quit Attempts Among Adults Living in 12 US States, 2015. Am. J. Health Promot. 2019, 33, 498–506.

12. Sakko, Y.; Madikenova, M.; Kim, A.; Syssoyev, D.; Mussina, K.; Gusmanov, A.; Zhakhina, G.; Yerdessov, S.; Semenova, Y.; Crape, B.L.; et al. Epidemiology of tuberculosis in Kazakhstan: Data from the Unified National Electronic Healthcare System 2014–2019. BMJ Open 2023, 13, e074208.

13. United States Department of Agriculture Economic Research Service. Food Security in the U.S.: Key Statistics & Graphics.

2021. Available online: https://www.ers.usda.gov/topics/food-nutrition-assistance/food-security-in-the-us/key-statistics-graphics (accessed on 23 March 2025).

14. Pierannunzi, C.; Hu, S.S.; Balluz, L. A systematic review of publications assessing reliability and validity of the Behavioral Risk Factor Surveillance System (BRFSS), 2004–2011. BMC Med. Res. Methodol. 2013, 13, 49. [ Central]

15. Mayer, M.; Gueorguieva, R.; Ma, X.; White, M.A. Tobacco use increases risk of food insecurity: An analysis of continuous NHANES data from 1999 to 2014. Prev. Med. 2019, 126, 105765.

16. Snelson, C.L. Qualitative and Mixed Methods Social Media Research: A Review of the Literature. Int. J. Qual. Methods 2016, 15, 1609406915624574.

17. Zhang, T.; Patil, S.G.; Jain, N.; Shen, S.; Zaharia, M.; Stoica, I.; Gonzalez, J.E. RAFT: Adapting Language Model to Domain Specific RAG. arXiv 2024, arXiv:2403.10131.

18. Creswell, J.W.; Poth, C.N. Qualitative Inquiry and Research Design: Choosing Among Five Approaches, 4th ed.; SAGE Publications: Thousand Oaks, CA, USA, 2016; ISBN 978-1-5063-6117-8.

19. Centers for Disease Control and Prevention. Statistical Brief on the Social Determinants of Health and Health Equity Module, Behavioral Risk Factor Surveillance System.

2022. Available online: https://restoredcdc.org/www.cdc.gov/brfss/data_documentation/pdf/SDOH-Module-Statistical-Brief-508c.pdf (accessed on 10 September 2024).

20. Chung-Hall, J.; Fong, G.T.; Meng, G. Evaluating the impact of menthol cigarette bans on cessation and smoking behaviors in Canada: Longitudinal findings from the Canadian arm of the 2016-18 ITC Four Country Smoking and Vaping Surveys. Tob. Control. 2022, 31, 556–563.

21. Zhussupov, B.; Hermosilla, S.; Terlikbayeva, A.; Aifah, A.; Ma, X.; Zhumadilov, Z.; Abildayev, T.; Darisheva, M.; Berikkhanova, K. Risk Factors for Primary Pulmonary TB in Almaty Region, Kazakhstan: A Matched Case-Control Study. Iran. J. Public Health 2016, 45, 441–450.

22. Centers for Disease Control and Prevention (CDC). National Center for Health Statistics (NCHS). In National Health Interview Survey; U.S. Department of Health and Human Services, CDC: Hyattsville, MD, USA, 2023.

Downloads

Published

2026-05-17

Issue

Section

Articles